About My Father centers around Sebastian (Maniscalco) who is encouraged by his fiancée (Leslie Bibb) to bring his immigrant, hairdresser father, Salvo (De Niro), to a weekend get-together with her super-rich and exceedingly eccentric family (Kim Cattrall, Anders Holm, Brett Dier, David Rasche). The weekend develops into what can only be described as a culture clash, leaving Sebastian and Salvo to discover that the great thing about family is everything about family.